… better measure of cross-linking capability of 1-nitroacridines than do the c25values, since
in the latter case, our description of DNA cross-linking by 1-nitroacridines may be complicated …

… I-nitroacridines exhibit exceptionally high cytotoxic activity and antitumor properties [1…
interstrand DNA crosslinking, the phenomenon responsible for biological activity of 1-nitroacridines …

… with Eat DNA [11,16] mdmated that, as an after-effect of mteractmn with a 1-mtroacndme, a …
This greater efficacy of Ledaknn m its cross-linking of B subtihs DNA becomes more apparent …

… of action of cytotoxic and antitumor 1-nitroacridines. III. In vivo interstrand cross-linking of DNA
… as an aftereffect of their interstrand DNA cross-linking. Cancer Res 44: 4289-4296, 1984. …

… the differences in cytotoxic activity among 1-nitroacridines as eg … seems to be an after-effect
accompanying DNA damage but of … In vivo interstrand cross-linking of DNA in mammalian or …

… of action of cytotoxic and antitumour 1-nitroacridines. III. In uioo interstrand cross-linking of
DNA … of I-nitroacridines as an after effect of their interstrand DNA cross-linking. Cancer Res 44: …

… The 1-nitroacridines do not exert their cytotoxic effects by … as an after effect of their
interstrand DNA crosslinking. … Skladanowski A, Konopa J (1994a) Interstrand DNA crosslinking …

… Imidazoacridinones (IA) are a class of antitumor agents which … to DNA for a series of 13
analogs that differ in their cytotoxic … The 1-nitroacridines do not exert their cytotoxic effects by …

… C-1873 with their cytotoxicity and their anti-tumor efficacy. The … 1-nitroacridines have been
synthesized that hold promise as … drugs to form inter-strand cross-links with DNA, which in the …

… In vivo interstrand cross-linking of DNA of mammalian or bacterial cells by … Cytotoxic
and antitumor activity of 1-nitroacridines as an aftereffect of their interstrand DNA cross-linking. …